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Hypothalamic PeptidesEndocrine ResearchπŸ”¬ RUO

Thyrotropin-Releasing Hormone (TRH)

Molecular Data

Formula

C16H22N6O4

Mol. Weight

362.38 Da

CAS Number

24305-27-9

Purity

β‰₯98% (HPLC)

Appearance

White lyophilized powder

Storage

-20Β°C, desiccated

Amino Acid Sequence

pGlu-His-Pro-NH2

Research Overview
TRH is a tripeptide hypothalamic hormone that stimulates TSH and prolactin release from the anterior pituitary.
Mechanism of Action
Binds TRH receptors (TRHR1/2) on thyrotrophs and lactotrophs, activating phospholipase C and calcium-dependent hormone secretion.
Research Applications
Thyroid axis physiology, pituitary function studies, neuroendocrine regulation, depression research, thermoregulation investigation.
Key Research Findings
Rapid TSH release within minutes of administration. CNS effects independent of thyroid axis modulation.
MANDATORY DISCLAIMER: Thyrotropin-Releasing Hormone (TRH) as referenced on this page is strictly for in-vitro laboratory research and forensic applications only. It is NOT for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction. Any reference to research outcomes pertains exclusively to controlled laboratory settings. Researchers must comply with all applicable local, state, and federal regulations.
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All compounds, peptides, and research materials referenced on peptidepepe.com are strictly for in-vitro laboratory research and forensic applications only.These products are NOT intended for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction.By proceeding, you confirm that you are a qualified researcher or represent a legitimate research institution, and you agree to use all information on this platform exclusively for lawful research purposes.