LABORATORY RESEARCH USE ONLY β This compound is NOT for human consumption, veterinary use, or therapeutic applications.
Melanocortin PeptidesPigmentation Research㪠RUO
Melanotan I (Afamelanotide)
Molecular Data
Formula
C78H111N21O19
Mol. Weight
1646.85 Da
CAS Number
75921-69-6
Purity
β₯98% (HPLC)
Appearance
White lyophilized powder
Storage
-20Β°C, desiccated, protected from light
Research Overview
Melanotan I (Afamelanotide) is a linear analog of Ξ±-MSH with enhanced stability. Unlike Melanotan II, it shows greater MC1R selectivity.
Mechanism of Action
Selective MC1R agonism stimulating eumelanin synthesis through cAMP-MITF-tyrosinase cascade in melanocytes.
Research Applications
MC1R-selective signaling, photoprotection research, erythropoietic protoporphyria modeling, melanocyte biology, UV damage prevention studies.
Key Research Findings
MC1R selectivity reduces off-target melanocortin effects. Significant eumelanin increase in melanocyte cultures.
MANDATORY DISCLAIMER: Melanotan I (Afamelanotide) as referenced on this page is strictly for in-vitro laboratory research and forensic applications only. It is NOT for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction. Any reference to research outcomes pertains exclusively to controlled laboratory settings. Researchers must comply with all applicable local, state, and federal regulations.
