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LL-37

Molecular Data

Formula

C205H340N60O53

Mol. Weight

4493.33 Da

CAS Number

154947-66-7

Purity

≥95% (HPLC)

Appearance

White lyophilized powder

Storage

-20°C, desiccated

Amino Acid Sequence

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser

Research Overview
LL-37 is the only human cathelicidin antimicrobial peptide. It is a 37-amino acid peptide cleaved from the C-terminus of the hCAP18 precursor protein.
Mechanism of Action
Disrupts microbial membranes through electrostatic interaction with anionic phospholipids. Also modulates innate immune responses and promotes wound research observation.
Research Applications
Antimicrobial mechanism studies, biofilm disruption research, innate immunity investigation, wound research observation models, cancer cell membrane studies.
Key Research Findings
Broad-spectrum antimicrobial activity against bacteria, fungi, and enveloped viruses. Biofilm disruption at sub-inhibitory concentrations.
MANDATORY DISCLAIMER: LL-37 as referenced on this page is strictly for in-vitro laboratory research and forensic applications only. It is NOT for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction. Any reference to research outcomes pertains exclusively to controlled laboratory settings. Researchers must comply with all applicable local, state, and federal regulations.
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All compounds, peptides, and research materials referenced on peptidepepe.com are strictly for in-vitro laboratory research and forensic applications only.These products are NOT intended for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction.By proceeding, you confirm that you are a qualified researcher or represent a legitimate research institution, and you agree to use all information on this platform exclusively for lawful research purposes.