LABORATORY RESEARCH USE ONLY — This compound is NOT for human consumption, veterinary use, or therapeutic applications.
Anti-Inflammatory PeptidesImmunology Research🔬 RUO
KPV
Molecular Data
Formula
C16H30N4O5
Mol. Weight
357.45 Da
CAS Number
67727-97-3
Purity
≥98% (HPLC)
Appearance
White lyophilized powder
Storage
-20°C, desiccated
Amino Acid Sequence
Lys-Pro-Val
Research Overview
KPV is a C-terminal tripeptide fragment of alpha-melanocyte stimulating hormone (α-MSH). Despite its small size, it retains significant anti-inflammatory properties.
Mechanism of Action
Enters cells and directly inhibits NF-κB nuclear translocation, suppressing pro-inflammatory cytokine expression (TNF-α, IL-6, IL-1β).
Research Applications
Inflammatory bowel disease modeling, NF-κB pathway studies, mucosal immunity research, topical anti-inflammatory investigation, gut barrier function.
Key Research Findings
Potent NF-κB inhibition despite minimal size. Oral bioavailability demonstrated in rodent colitis models.
MANDATORY DISCLAIMER: KPV as referenced on this page is strictly for in-vitro laboratory research and forensic applications only. It is NOT for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction. Any reference to research outcomes pertains exclusively to controlled laboratory settings. Researchers must comply with all applicable local, state, and federal regulations.