LABORATORY RESEARCH USE ONLY β This compound is NOT for human consumption, veterinary use, or therapeutic applications.
Longevity & Anti-AgingNeuroprotection Research㪠RUO
Humanin
Molecular Data
Formula
C116H185N37O34S2
Mol. Weight
2687.00 Da
CAS Number
N/A
Purity
β₯95% (HPLC)
Appearance
White lyophilized powder
Storage
-20Β°C, desiccated
Research Overview
Humanin is a 24-amino acid mitochondria-derived peptide encoded in the 16S rRNA gene. It was discovered through its ability to suppress neuronal cell death.
Mechanism of Action
Binds IGFBP-3 and BAX, inhibiting intrinsic apoptosis. Also activates STAT3 signaling through the CNTFR/WSX-1/gp130 receptor complex.
Research Applications
Neuroprotection studies, mitochondrial-derived peptide biology, apoptosis regulation, Alzheimer's disease modeling, cytoprotection research.
Key Research Findings
Potent suppression of amyloid-beta-induced neuronal death. STAT3 activation provides broad cytoprotective effects.
MANDATORY DISCLAIMER: Humanin as referenced on this page is strictly for in-vitro laboratory research and forensic applications only. It is NOT for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction. Any reference to research outcomes pertains exclusively to controlled laboratory settings. Researchers must comply with all applicable local, state, and federal regulations.
