LABORATORY RESEARCH USE ONLY β This compound is NOT for human consumption, veterinary use, or therapeutic applications.
Senolytic PeptidesAging Researchβ Featuredπ¬ RUO
FOXO4-DRI
Molecular Data
Formula
D-retro-inverso peptide
Mol. Weight
4800.00 Da
CAS Number
N/A
Purity
β₯95% (HPLC)
Appearance
White lyophilized powder
Storage
-20Β°C, desiccated
Research Overview
FOXO4-DRI is a D-retro-inverso peptide designed to disrupt the FOXO4-p53 interaction in senescent cells. It represents a targeted senolytic approach.
Mechanism of Action
Competitively disrupts FOXO4-p53 binding in senescent cells, releasing p53 to the mitochondria and triggering intrinsic apoptosis selectively in senescent cells.
Research Applications
Cellular senescence research, senolytic mechanism studies, aging biology, p53 pathway investigation, tissue rejuvenation modeling.
Key Research Findings
Selective apoptosis of senescent cells without affecting proliferating cells. Improved physical function markers in aged rodent models.
MANDATORY DISCLAIMER: FOXO4-DRI as referenced on this page is strictly for in-vitro laboratory research and forensic applications only. It is NOT for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction. Any reference to research outcomes pertains exclusively to controlled laboratory settings. Researchers must comply with all applicable local, state, and federal regulations.
