LABORATORY RESEARCH USE ONLY β This compound is NOT for human consumption, veterinary use, or therapeutic applications.
Myostatin InhibitorsMuscle Research㪠RUO
ACE-031
Molecular Data
Formula
Fc fusion protein
Mol. Weight
115000.00 Da
CAS Number
N/A
Purity
β₯95% (SEC-HPLC)
Appearance
Clear solution
Storage
2-8Β°C
Research Overview
ACE-031 is a soluble form of activin receptor type IIB (ActRIIB) fused to an IgG1 Fc domain. It acts as a ligand trap for myostatin and related TGF-Ξ² superfamily members.
Mechanism of Action
Sequesters myostatin, activin A, GDF-11, and other TGF-Ξ² ligands, preventing their binding to endogenous ActRIIB and removing the brake on muscle growth.
Research Applications
Myostatin inhibition studies, muscle wasting research, neuromuscular disease modeling, TGF-Ξ² superfamily pharmacology, sarcopenia investigation.
Key Research Findings
Significant muscle mass increases in preclinical models. Broader ligand trapping than myostatin-specific antibodies.
MANDATORY DISCLAIMER: ACE-031 as referenced on this page is strictly for in-vitro laboratory research and forensic applications only. It is NOT for human consumption, veterinary use, diagnostic purposes, therapeutic applications, or any form of bodily introduction. Any reference to research outcomes pertains exclusively to controlled laboratory settings. Researchers must comply with all applicable local, state, and federal regulations.